GABA transporter - significado y definición. Qué es GABA transporter
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Qué (quién) es GABA transporter - definición


GABA transporter         
  • The cartoon depicts a GABAergic synapse in adult rat brain where GABA is released exocytotically and acts upon specific post-synaptic receptors. The signal is terminated by removal of GABA from the synaptic cleft by transport of GABA back into the nerve terminal by the plasma membrane GABA transporter (GAT) 1.
  • Molecular phylogenetic analysis of the SLC6 neurotransmitter transporter family in ''Homo sapiens''
  • Secondary structure and surface representation of LeuTAa. Topology of Aquifex aeolicus LeuTAa. The transporter is composed of 12 trans-membrane regions with cytoplasmic N- and C-terminal domains. TM1 and TM6 are oriented antiparallel to one another and have breaks in their helical structure approximately halfway across the membrane bilayer. The transporter has two extracellular β-strands (green arrows), four extracellular and two intracellular helices
GABA transporters (Gamma-Aminobutyric acid transporters) belong to the family of neurotransmitters known as sodium symporters, also known as solute carrier 6 (SLC6). These are large family of neurotransmitter which are Na+ concentration dependent.
GABA transporter type 2         
FAMILY OF TRANSPORT PROTEINS
GABA transporter 2
GABA transporter 2 (GAT2; SLC6A13) also known as sodium- and chloride-dependent GABA transporter 2 is one of four GABA transporters, GAT1 (SLC6A1), GAT2 (SLC6A13), GAT3 (SLC6A11) and BGT1 (SLC6A12). Note that GAT2 is different from BGT1 despite the fact that the latter transporter is sometimes referred at as (mouse) GAT-2.
GABA transporter type 3         
MAMMALIAN PROTEIN FOUND IN HOMO SAPIENS
GABA transporter 3; SLC6A11
GABA transporter type 3 (GAT3) uses sodium (Na+) electrochemical gradients to mediate uptake of GABA from the synaptic cleft by surrounding glial cells.